The short term physical effects of LSD include nausea, increased blood sugar, dilated pupils, raised body temperature, and sleepiness.

 

The drug can cause significantly impaired decision making and coordination. People under the influence of LSD suffer from distorted perceptions of depth, movements, colors, and time

 

After long periods of repeated use, LSD users develop a tolerance to the drug. This can cause many long term physical effects including hyperthermia, heart failure, and significantly impaired judgement potentially leading to death.